The poly-pill approach to health care ...

"A "polypill" packed with four different medications to treat high blood pressure and cholesterol can cut the risk of heart attacks and strokes by up to 40 per cent when taken with aspirin, a study has suggested." 

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	aspirin (75 mg), for thinning the blood lisinopril (10 mg), for reducing blood pressure hydrochlorothiazide (12.5 mg), also for reducing blood pressure simvastatin (20 mg), for reducing “bad” LDL cholesterol

 

Does it follow then (triage aside) that in our health and social care interventions we should not restrict ourselves to a single care domain?

 

My source: 

News: 'Polypill' with aspirin offers hope of fewer heart attacks, The Times, 14 November, 2020, p.28.

 

See also:

https://blogs.bmj.com/bmj/2020/11/16/richard-smith-a-new-important-study-supports-wider-use-of-the-polypill/

PRIMEtime CE: a multistate life table model for estimating the cost-effectiveness of interventions affecting diet and physical activity

When I saw Adam Brigg's tweet and thread the figure below stood out.

I have modelled some of the concepts using Hodges' model. I have added some additions, flagging gender* to highlight way this and other factors (often) need to be considered in a multicontextual manner.

There is a lot more of course, including the reference list; for example Squires, et al. which pose some interesting questions.

81. Squires H, Chilcott J, Akehurst R, Burr J, Kelly MP. A framework for developing the structure of public health economic models. Value Health. 2016;19:588–601.

Fig. 1 The PRIMEtime CE conceptual model

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Interventions over time individual behaviours motivation	model: outputs AGE, GENDER* Active People Survey DIET - PHYSICAL ACTIVITY cardio-vascular disease - heart disease,  stroke, diabetes,  liver disease, cancers, raised blood pressure, cholesterol, and body weight TIME: chronological-pathological PROCESS
PRACTICE behaviours - social over time social care socio -	population health POLICY health economics health care costs social care costs return on investment - economics

My source (and do follow Adam's full-thread):

2/
The first paper is here. It describes the PRIMEtime CE model.

This builds on @Pete_Scarbs and Linda Cobiac's work on the PRIMEtime model (and PRIME before then). My contribution was to add utilities + health & social care costs.https://t.co/B0Fu9uP4ru pic.twitter.com/aGaMcpwIks

— Adam Briggs (@ADMBriggs) July 17, 2019

Patient Education: Stable - Unstable Plaques c/o twitter ...

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'The patient' Insight, Awareness, Understanding Attention, Engagement, Recall Health Literacy	Stable-Unstable Plaques Statins Post Myocardial Infarction Evidence-Based Care
Love this unstable plaque explanation - why this man should take a statin post MI @Channel4 #GPsBehindClosedDoors - please namecheck this nurse if you know her @theRCN @RCNconnects @NursingTimes @TheBHF @BritishCardioSo @DrPascalMeier @Heart_BMJ @JACCJournals #medshr pic.twitter.com/r1t0VCL0SL — Dr Asif Qasim (@DrAsifQasim) December 5, 2018	Policy Post MI Intervention or Pre MI? Clinics ('Real time'?) Public Health Funding

ERCIM News No. 108 Special theme: "Computational Imaging"

Dear ERCIM News Reader,

ERCIM News No. 108 has just been published at http://ercim-news.ercim.eu/en108

This issue features:

ERCIM News 108

• A Special Theme "Computational Imaging" with 21 articles providing an insight in the many complex facets of computational imaging, coordinated by the guest editors Joost Batenburg (CWI) and Tamas Sziranyi (MTA SZTAKI) .
• Keynote "Imaging as a Ubiquitous Technique: New and Old Challenges" by Andy Götz, Head of Software at European Synchrotron Radiation Facility and Armando Solé, Head of Data Analysis at European Synchrotron Radiation Facility
• A "Research and Innovation" section with news about research activities and innovative developments from European research institutions

This issue is also available for download in pdf and ePUB

Thank you for your interest in ERCIM News. Feel free to forward this message to others who might be interested.

Next issue: No. 109, April 2017 Special Theme: "Autonomous Vehicles"

Best regards,
Peter Kunz
ERCIM News editor in chief

Loneliness: across the Domains c/o BMJ

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isolation loneliness mental health feelings  identity  meaning motivation - behaviour SUBJECTIVITY	physical health, coronary heart disease , stroke mortality longitudinal observational studies meta-analysis systematic review OBJECTIVITY
social network  family - relationships - befriending social isolation quality of life family - community cohesion social enterprise SOCIO-	policy social care provision day centers mobility - transport volunteering public - funding - private economic

Valtorta, N.K., Kanaan, M., Gilbody, S., et al. (2016). Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies. Heart. Published Online First: [April 18, 2016]. doi:10.1136/heartjnl-2015-308790

My original source:
Smyth, C. Warning: loneliness as bad for your health as tobacco & Scourge of Loneliness. The Times, 20 April 2016, p.4 and 20.