Hodges' Model: Welcome to the QUAD: cells

Hodges' model is a conceptual framework to support reflection and critical thinking. Situated, the model can help integrate all disciplines (academic and professional). Amid news items, are posts that illustrate the scope and application of the model. A bibliography and A4 template are provided in the sidebar. Welcome to the QUAD ...

Showing posts with label cells. Show all posts
Showing posts with label cells. Show all posts

Friday, March 01, 2024

'Writing Samer'

Molly Fairhurst
 

... across the domains

"Diagnosed with a terminal cancer, Samer Iskandar couldn't find the words to describe what he was living through. Instead, he proposed an unusual collaboration." p.33.

 


Individual
   |
      INTERPERSONAL    :     SCIENCES               
HUMANISTIC  --------------------------------------  MECHANISTIC      
 SOCIOLOGY  :   POLITICAL 
|
Group

"Samer's cancer^ is like all cancers in that it pitches the self into a battle against the non-self, - *


"Memory, language, attention and cognition all erode to ultimately leave you somewhere east of your prior self and west of someone new." p.34.




- atavistic alien cells invading their host from within. But it is unlike most cancers in how directly this cellular plunder correlates to the personal one." 

It is like all cancers in that its lexical field is that of topography, malignancies spreading, diffusing and gaining ground. It is unlike them in that these movements are finally technical, gears cramped within the clock of a terminal diagnosis." p.34.





^glioblastoma
*discuss

Youmna Melham Chamieh, Writing Samer, FT Weekend Magazine, 24/25 February, 2024, Issue 1,062, pp.32-37.

Illustrations by Molly Fairhurst
https://mollyfairhurst.com/Financial-Times (above source).

Friday, November 18, 2022

The politics of 'real' power: Mitochondria

 INDIVIDUAL
|

 INTERPERSONAL    :     SCIENCES               
HUMANISTIC --------------------------------------  MECHANISTIC      
SOCIOLOGY  :   POLITICAL 
|
GROUP







The Climate Book

See also:

Book: The Vital Question

My source: Whipple, T. Where all life begins - the magic of cells, Saturday Review, The Times, November 5, 2022, p.16-17. Blakely, R. The Greta Thurnberg guide to saving the planet (same pages).

Wednesday, September 14, 2022

Yes, size matters

 INDIVIDUAL
|
 INTERPERSONAL    :     SCIENCES               
HUMANISTIC --------------------------------------  MECHANISTIC      
SOCIOLOGY  :   POLITICAL 
|
GROUP


Hammond, G. 'The mini market'. House&Home, City Living Special, FTWeekend, 4-5 May 2019, pp.8-9.
https://www.ft.com/content/03a9343e-6b35-11e9-80c7-60ee53e6681d





This morning I shared three slides with the PAMHOP research team and greatly appreciate the opportunity to present and join their meeting:

Physical and Mental Health of Older Prisoners (PAMHOP)

As I spoke of considering the environment and the carceral context across the domains of the model, I recalled another piece of paper.

The image above is from FTWeekend in 2019.

In prison of course, while the physical environment is the intended constraint, the model also invites consideration of the psychological, social, political environments and added here - the spiritual.

Since 2019 and post-COVID, the change in how we regard and value the spaces we inhabit - voluntarily or otherwise.

Hammond, G. 'The mini market'. House&Home, City Living Special, FTWeekend, 4-5 May 2019, pp.8-9. https://www.ft.com/content/03a9343e-6b35-11e9-80c7-60ee53e6681d

The image above was copied from FTWeekend and pasted into a new image and saved from avif format to .jpg.

 

Friday, July 22, 2022

Henrietta Lacks' 'immortal cells'

INDIVIDUAL
|
 INTERPERSONAL    :     SCIENCES               
HUMANISTIC --------------------------------------  MECHANISTIC      
SOCIOLOGY  :   POLITICAL 
|
GROUP

Henrietta


'immortal cells'

Lacks





No consent
No family knowledge

Harm to trust of African American communities
Damage to trust in medical research generally



Thanks to Ilaria Galasso, for reminding me about HeLa cells - Henrietta Lacks in a presentation at:

https://vitalcirculations.org/

15:00-15:30 Genetic data and the collective good: participants as leaders to reconcile individual and public interest | Ilaria Galasso

https://www.eventbrite.co.uk/e/vital-circulations-vital-data-symposium-tickets-365908681717

 

 


Monday, May 02, 2022

Review ii - "Brainscapes: The Warped, Wondrous Maps Written in Your Brain―And How They Guide You"

Brainscapes

Now I know how Umami (p.87) an "example food magazine website to demonstrate some of the features of Drupal core" - got its name. I'm sure this was explained at a Drupal Meetup. Savoury indeed!

There had to be two! The brain has two strategies: brain maps and distributed codes.

"Representing information with a distributed code is entirely different from representing it with brain maps. In a brain map, neighboring neurons represent neighboring regions in space, frequency, time, and so forth. And brain maps essentially represent information using location, or where in the brain area the neurons are most active. In contrast, there is no consistent relationship between neighboring neurons in brain areas that use distributed codes. These areas represent information through the distributed pattern of activity across that entire region of the brain, rather than through the location of activity within it. This pattern of activity is a kind of code." pp.93-94.

This distinction is significant for Hodges' model, as the distributed codes act to deal with novelty, what is new - ongoing (lifelong) learning (p.95). Hodges' model can help distinguish between subjective and objective concerns. Schwarzlose unifies the two - via a catfish (also a goal here - but not necessarily with such an assistant).

"The map in the olfactory bulb is organised into odor zones based on molecular structure, an objective property of these compounds in the physical world. But the second map is organized into zones based on the significance of the odors to the animal." p.100.

Chapter 6 'On the Move: Brain Maps for Action' would have been useful as a student nurse at Winwick Hospital, the history in the book brings back many reminders - late 1970s. Epilepsy, then was less well understood, and managed. In describing the M1 brain map and movement I wondered about consent, but can see that is a distraction. Chapters -

6. On the Move: Brain Maps for Action | 107
7. Maps in the Making: How Brain Maps Develop and Adapt | 131
8. Knowing Again: Brain Maps for Recognition | 151
- offer much to relate to clinical encounters: movement, reaching, infant versus the brain in adults, the senses and catastrophic events such as cerebrovascular accident - stroke. Morphologically there is much still to learn (brain maps are 'primed' before birth), which perhaps is why we recognise the remarkable nature of gestation and birth. 'Maps in the Making' provides wondrous insights, including the need in hospitals to rethink the sensory environment and experience for premature infants.

While reading - I was struck at the experience of the newborn and mothers in Ukraine. The 'health career' model concerns life chances - from birth to later life...

As a community mental health nurse I have found subtle and less-subtle impacts on a person affected by semantic dementia (p.204) and their family. Given the ongoing invasion and war, I also thought about people living with dementia and having to flee their homes. The multiple contexts that pertain in such a crisis situation when considering 'maps' and sense-making. Especially, when the need for action is preemptive - preventive and so must be explained and justified, not once but perhaps repeatedly?

We are all innate mathematicians even if we feel we have no ability. 

https://www.google.com/search?client=firefox-b-d&q=mathematics+in+catching+a+ball

I take some succor in this (p.127).

There's a hodgepodge in here too (p.161 hb). The myriad of objects we encounter and their recognition calls for the combination of brain maps and distributed codes. Chapter 8 is more psychological, touching :-) how we categorise objects, dimensions and scales, size and animacy. Galton's contribution is discussed, his ideas on eugenics also acknowledged. Visual perception, mental imagery and visual learning style remain subjects of note for researchers. I'm not sure why figure 32 stood out ( :-) - please pardon the quality of the photo. Paul Kim's illustrations are an excellent support for the prose.):

FIGURE 32 A comparison of visual perception and mental imagery in
the V1 visual map. Paul Kim

Somewhere I've saved an article on mental imagery from New Scientist I think, about this ability - the mind's eye and how it is missing for some 'brilliant' people (p.182) and posted previously:

In my mind's eye I can picture care: Frame by Frame

I might read Chapter 9 again, attention, action and perception in combination. 

Chapter 10 had me thinking again about 'Conceptual Spaces' (quality dimensions) and threshold concepts (not in the book - but this is a positive!):

"Many of the concepts that rule our financial, social, and emotional well-being have no shape, no color, no odor or weight. How do we grasp these intangible concepts? As it turns out, we often do so by aligning abstract concepts with physical dimensions and then putting our brain maps to work." p.191.

There is a 'mental number line', vertical too, and culture is a factor in how we learn and the brain associates space and quantities, in which L-R, low-high are also brought into play. The question remains here: Is Hodges' model culturally neutral? 

Still with h2cm - mind reading, writing and 'drawing' perhaps? p.236. In "Fortune-Telling with the Brain" we read about how fMRI is allowing us to learn how the brain maps employ teamwork. There is an architecture whose stability can inform predictions of future abilities - reading is described. Reading this you see ethical implications (as Schwarzlose warns p.238), but it may help to target personalised learning, as an adjunct to personalised medicine? I double checked (index) and the connectome is not mentioned, but the benefits of this research is still to be realised. In 'prison health' here in the UK (and globally?) it is long overdue but it is encouraging to hear about the focus on investigation for previous brain injury within the prison population. Remember - lead in fuel and the socio-economic impacts of pollution (ongoing - air and plastic pollution)?

Corporations have literally only 'scratched the surface' of the future potential to 'read' us individually. Through Hodges' model I can qualify and justify the model's increasing relevance. Technology and science not only call for SOCIO-technical approaches. The brain-computer interface and AI (p.239) demands we also consider the several forms of literacy and informatics that are needed in the 21st century: bio-informatics, bio-political, psycho-political and more.

This is very informative and timely read - the diagrams too. This is a book for all. For student nurses specifically, it will enable them to maximize learning in their practical placements and throughout their course of study.

Writing this review I can also see the important messages in chapter 12 - recognition of infancy and the opportunities this affords.

Many thanks to Rebecca Schwarzlose and Profile Books for my review copy.

Schwarzlose, R. (2021) Brainscapes: The Warped, Wondrous Maps Written in Your Brain―And How They Guide You". London: Profile Books.

Thursday, April 28, 2022

Review i - "Brainscapes: The Warped, Wondrous Maps Written in Your Brain―And How They Guide You"

Brainscapes

 

A marvellous cover (US too), a fascinating, clearly written and hence readable book. As expected today the layout, print size and design add enjoyment to the time invested.

As a nurse with an interest in science you are aware of much of the content in broad terms but 'Brainscapes' provides more detail and made me wonder about the prospects to follow from improvements in brain imaging, The Connectome, new technologies and techniques. Rebecca maintains the focus throughout.

I'm pleased to add this to my CPD reading list.

Nature and science are humbling. It is still quite recent that we realised the milky way is one of billions of galaxies. Now we can appreciate not only the complexity of the brain, but how it is embodied in mind, body and our experience of reality.

There is history here to begin. Russia and Japan were at war in 1904. Russia had a new high-velocity rifle with smaller bullets, 7.6mm reaching speeds of 620 meters per second. Whether co-incidence, and/or ironic, there are of course many brains trying to make sense of the current conflict in Eastern Europe. A change in injuries followed with these bullets capable of passing straight through the skull, sparing the life of the soldier and yet with life altering injuries. 

As triage was founded on the battle-ground. So aftercare is grounded in the journey back 'home' for those who can make it and the extent to which 'veterans' and their families are recognised.* This lead to investigations (Inouye, see below) as soldiers experienced localised damage to the brain. Soldiers suffered scotomas affecting their vision, stimulating research and new approaches, devices 'cranio-coordinometer'. There are illustrations and some photographs throughout, the illustrator Paul Kim, adding to the text.

In 'Maps of You' maps are everywhere especially on screens, and yet as Schwarzlose notes the map's materials matter little. On p.17 "All I need is a pen and a scrap paper" I smiled - given the 'map' that Hodges' model provides, on paper, sand, black/whiteboard and mind's eye. Mental imagery is there too. Salience, figures early p.19 and with brain maps, visual maps and where we direct our gaze prompts more detailed consideration of context. The explanations of the sensory brain maps is fascinating, especially how the brain has evolved to deal with constraints of space, energy, distance and organisation. At the fovea in the eye, the map is magnified. 

Perhaps in Hodges' model there are two fovea? One is the center of the model, the person-centred nexus an assurance function/correction as the fovea that is context shifts and jumps in response to the dynamics of the situation. Reading about the audio map, p.73 I thought about the 'timbre of care' (Yes, I've a bad case of h2cm-meme-mapitis). As a further sign of the times, chapter 5 (A Body Under Siege) on taste and smell and the protective function of what we do or don't ingest, I travelled from the individual to the national and the binary choices (yes or no) being exercised right now.

More to follow ...

Alexander P. Leff (2015) Tatsuji Inouye (1881–1976), Discovery UCL.
https://discovery.ucl.ac.uk/id/eprint/1491645/1/Leff_tatsuji_inouye_1881-1976.pdf

Many thanks to Rebecca Schwarzlose and Profile Books for my review copy.

*Apologies for digression...

Thursday, October 11, 2018

FROM: Cell TO: Street

individual
|
INTERPERSONAL : SCIENCES
humanistic ----------------------------------------------- mechanistic
SOCIOLOGY : POLITICAL
|
group

cell *

cell

street

CELL


Prison Leavers, Prison Reform Trust

Advice for prisoners and ex-offenders, Shelter


*Monastic cell

 

Tuesday, July 11, 2017

Book: The Vital Question

individual
|
INTERPERSONAL : SCIENCES
humanistic --------------------------------------- mechanistic
SOCIOLOGY : POLITICAL
|
group
Book:
THE VITAL QUESTION
"We are nothing special. Bacteria such as E coli can divide every 20 minutes. To fuel its growth E coli consumes about 50 billion ATPs per cell division, some 50-100 times each cell's mass. That's about four times our rate of ATP synthesis. Convert these numbers into power measured in watts and they are just as incredible. We use about 2 milliwatts of energy per gram - or some 130 watts for an average person weighing 65kg, a bit more than a standard 100 watt light bulb. That may not sound like a lot, but per gram it is a factor of 10,000 more than the sun (only a tiny fraction of which, at any moment, is undergoing nuclear fusion). Life is not much like a candle; more a rocket launcher." p. 64.





Lane, N. (2015) The Vital Question: why is life the way it is? London: Profile Books. p.64 (Paperback)

Friday, June 30, 2017

Book: Selfie

individual
|
INTERPERSONAL : SCIENCES
humanistic ----------------------------------------- mechanistic
SOCIOLOGY : POLITICAL
|
group - population

Cellfie image: The Telegraph

Saturday, November 12, 2016

Triangulation: c/o Roger Ballen

individual
|
INTERPERSONAL : SCIENCES
humanistic -------------------------------------------  mechanistic
SOCIOLOGY : POLITICAL
|
group-population
Triangulation: (c) Roger Ballen





Triangulation: (c) Roger Ballen


© 2016 Roger Ballen

The Theatre of Apparitions

My source and original image (top):
Jackson, K. Snapshots Primitive power in black and white. The New Review, The Observer, 30 October 2016. p.5.

https://www.theguardian.com/artanddesign/gallery/2016/oct/29/through-a-glass-darkly-roger-ballens-theatre-of-apparitions-in-pictures