Hodges' Model: Welcome to the QUAD: Mechanisms, Individuals and Collective

Hodges' model is a conceptual framework to support reflection and critical thinking. Situated, the model can help integrate all disciplines (academic and professional). Amid news items, are posts that illustrate the scope and application of the model. A bibliography and A4 template are provided in the sidebar. Welcome to the QUAD ...

Thursday, March 31, 2022

Mechanisms, Individuals and Collective

Last week I joined a webinar:
 
https://www.biokoinos.org/events
BioKoinos Research Seminar

Saúl Pérez González & Elena Rocca - 
Evidence-based and patient-centred clinical practice. The bridging role of evidence of mechanism.
  
I have mapped some of the concepts to Hodges' model. A link to the paper is included below. The session was very helpful, especially with ongoing developments in genomics and personalised medicine.
 
INDIVIDUAL
|
 INTERPERSONAL    :     SCIENCES               
HUMANISTIC --------------------------------------  MECHANISTIC      
SOCIOLOGY  :   POLITICAL 
|
GROUP
patient-centred
evidence
safety of a certain intervention
for a particular patient
safety
efficacy

individual - epidemiology - population
patient-centred
evidence
safety of a certain intervention
for a particular patient
biology
pathophysiological mechanism
prediction

... confirming and disconfirming -
depending on whether or not it supports that certain epidemiological results apply
to the single patient.

evidence
safety
efficacy

evidence
safety
efficacy


Pérez-González, S., & Rocca, E. (2022). Evidence of Biological Mechanisms and Health Predictions: An Insight into Clinical Reasoning. Perspectives in Biology and Medicine 65(1), 89-105.  

http://philsci-archive.pitt.edu/20364/1/Postprint%20Evidence%20of%20biological%20mechanisms%20and%20health%20predictions.pdf