Hodges' Model: Welcome to the QUAD: Tracking the Alzheimer's-Down syndrome connection

Hodges' model is a conceptual framework to support reflection and critical thinking. Situated, the model can help integrate all disciplines (academic and professional). Amid news items, are posts that illustrate the scope and application of the model. A bibliography and A4 template are provided in the sidebar. Welcome to the QUAD ...

Friday, April 16, 2021

Tracking the Alzheimer's-Down syndrome connection

individual
|
INTERPERSONAL : SCIENCES
humanistic ----------------------------------------------- mechanistic
SOCIOLOGY : POLITICAL
|
group

Communication, speech
self expression
personhood
identity
memory
personality
mood
Extend meaningful quality of life
Age 40
most people with Down syndrome develop beta amyloid plaques in the brain — a key characteristic of Alzheimer’s disease. Scientists believe this is because they have an extra copy of chromosome 21, which carries an amyloid-producing gene.Major international research effort, (ages 25+) plus siblings over five years.
Multisite Alzheimer’s Biomarkers Consortium — Down Syndrome (ABC-DS) study
Biomarkers, genetic background, environmental, metabolic and other physiological factors

Intergenerational angst
if parent/family member a primary carer?
Help families prepare for what’s going to happen potentially with their loved one

Funded by a $109 million grant
from the National Institutes of Health

 My source:

 Learn more about the study at mind.uci.edu/adrc/about