Hodges' Model: Welcome to the QUAD: antipsychotics

Hodges' model is a conceptual framework to support reflection and critical thinking. Situated, the model can help integrate all disciplines (academic and professional). Amid news items, are posts that illustrate the scope and application of the model. A bibliography and A4 template are provided in the sidebar. Welcome to the QUAD ...

Showing posts with label antipsychotics. Show all posts
Showing posts with label antipsychotics. Show all posts

Sunday, August 17, 2025

TDS - 'Tariff Derangement Syndrome' ...

... is that all you have to worry about?


Individual
|
      INTERPERSONAL    :     SCIENCES               
HUMANISTIC  --------------------------------------  MECHANISTIC      
 SOCIOLOGY  :    POLITICAL 
|


Vasan S, Padhy RK. Tardive Dyskinesia. [Updated 2023 Apr 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK448207/

Morrison PD, Jauhar S, Young AH. The mechanism of action of clozapine. Journal of Psychopharmacology. 2025;39(4):297-300. doi:10.1177/02698811251319458

Taylor D, Watanabe K. Tardive dyskinesia: understanding current challenges in diagnosis and treatment. Therapeutic Advances in Psychopharmacology. 2023;13. doi:10.1177/20451253221144347

'syndrome'?

Jablonski S,  Syndrome--a changing concept. Bulletin of the Medical Library Association. 1992;80(4), 323–327.

Calvo F, Karras BT, Phillips R, Kimball AM, Wolf F. Diagnoses, syndromes, and diseases: a knowledge representation problem. AMIA Annu Symp Proc. 2003;2003:802. PMID: 14728307; PMCID: PMC1480257.

Previously: 'psychosis' : 'mental illness'

My prompt: Claire Jones. Trump picks Powell critic and rates ally for Fed board. FTWeekend. 9-10 August 2025, p.6.

Thursday, September 01, 2022

Update on draft papers ;-)

Please excuse the intended irony, as need for an - 'update' could refer to far more than papers.*

Across the life of W2tQ (since April 2006...) there are many posts about papers by other people, papers planned and less frequently work published

A paper that started in 2017 has finally been accepted and we (not the Royal variety - which is a critical joy) await the proof. 

I'm really grateful to my co-author who stayed the course on what has been an utter roller-coaster and with COVID too. I look forward to sharing details and hence news of their ongoing research elsewhere - in Europe.

Another paper conceived in March has progressed more rapidly. With the initial draft well received, I'm addressing some revisions from editors, which are straightforward. 

I still need to 'see' these two birds in my hands, to believe: it will be worth it (I think?) to add these to the bibliography, as:

  • SDGs are fundamental in global health and reveal the scope and relevance of h2cm;
  • nutrition is critical in public (mental) health, policy and sustainability;
  • there is more to follow from the 'mapping' that is exercised on W2tQ [2x2 HTML tables thus far], in these, and other papers;
  • the psychoses constitute a severe mental health condition that can also illustrate the impact on individuals, friends, family and society;
  • in health (and social) care we must address parity of esteem in and across theory, practice, management, policy, and research;
  • how do (research) methods figure in Hodges' model (a mapping approach);
  • what does a similar mapping of cardiovascular medicine and nursing reveal?

These bibliographical additions may help researchers in health, social care, and other fields find the model. While it is disappointing to find out about papers that reference h2cm 'after the writing' this still counts. It is a reference, not a collaboration! This is very welcome and a key purpose of the blog, and presence - @h2cm - on twitter. 

It would be validating, so 'me' [massaging ego] but it would also be contradictory. 

Hodges' model is simple, isn't it? 

In its basic form, blank and template - it presents virgin territory for the user(s) to overlay with their map according to context.

I'll post again about three remaining drafts papers, one dates back to 2012 (I was full-time then) and one that is in two parts. I've learnt a lot (again) with the two 'nearbies' and will post and list details when able. 

If I can help you, your project - I'd be pleased to do so.

*a website for example!

See also: the blog's bibliography in the sidebar, plus -

'New' citation: "Pratique en milieu de psychiatrie légale: proposition d’un modèle interdisciplinaire."

Sunday, June 02, 2019

Friday, December 14, 2018

Study: Measuring Different Types of Relationship Styles in Psychosis

Division of Psychology and Mental Health
2nd Floor, Zochonis Building
The University of Manchester
Brunswick Street
Manchester
M13 9PL

Participant Information Sheet

Measuring Different Types of Relationship Styles in Psychosis

You are being invited to take part in a research study developing a questionnaire to measure different types of relationship styles in psychosis. Before you decide whether or not you would like to take part in the study, please read the following information carefully so that you can understand what taking part would involve for you. Then click the button at the bottom of the page to continue. If you have any questions or queries about taking part in the study, please contact the principal investigator, Catherine Pollard (catherine.pollard AT postgrad.manchester.ac.uk). You do not have to make a decision straight away, so if you have any doubts or feel unsure please take some time to think it over.

What is the study about?

Our early relationships have been linked to the development of psychosis, a mental health problem that means people interpret things differently from those around them. Psychosis involves experiences such as hallucinations, where a person hears, sees and in some cases feels, smells or tastes things that are not there; or delusions, where a person has strong beliefs that are not shared by others.

When people are young, they develop a sense of how they relate to themselves, others and the world. This includes how others relate to them. Some people grow up seeing their parent/guardian as fearful. Research suggests that when these young people grow up they are more likely to report hearing voices and feel paranoid. However, it is not clear how this happens.

At the moment, it is difficult to understand why these people are more likely to hear voices and feel paranoid. Therefore, more research needs to be done. We aim to develop a questionnaire that measures whether people have grown up feeling scared of their parent/guardian so that we can use this in research to help us understand the link between feeling fearful in early relationships and the development of psychosis.

This study will not directly offer you any benefit, but the study addresses a gap in psychosis research. Our work will help to understand the development of unusual experiences and help us develop more treatments for distressing experiences.

Please CONTINUE READING...



individual
|
INTERPERSONAL : SCIENCES
humanistic ----------------------------------------------- mechanistic
SOCIOLOGY : POLITICAL
|
group
SELF
beliefs
early relationships 
lived experiences
sensory experiences -
hear, see, feel, smell, taste ...
hallucinations, delusions
psychosis, distress, trauma

Confident with


WORLD
Involved in major accident
antipsychotic medication
Diagnosis 
Evidence-base
Measures

English language

OTHERS
social environment
parent(s), guardian, significant others
fear, traumatic loss of other
 Therapeutic input: CBT, Psychologist


WORLD

Treatment in a Mental Health
Unit / Hospital
Input from Community Mental Health Team or Early Intervention Service

subjective ------------------------------------------------------------------------------------- OBJECTIVE
qualitative -------------------------------------------------------------- QUANTITATIVE


My source:
@HearingVoicesUK & @RSInPsychosis
https://twitter.com/HearingVoicesUK/status/1073647206685663232

Monday, September 04, 2017

Ethical concerns: Four principles approach (in Hodges' model)

individual
|
INTERPERSONAL : SCIENCES
humanistic --------------------------------------- mechanistic
SOCIOLOGY : POLITICAL
|
group
autonomy
non-maleficence
beneficence
justice


Noordraven, E.L., Maartje H. N. Schermer, M.H.N., Blanken, P., Mulder, C.L. & Wierdsma, A.I. (2017). Ethical acceptability of offering financial incentives for taking antipsychotic depot medication: patients’ and clinicians’ perspectives after a 12-month randomized controlled trial. BMC Psychiatry, 17: 313. https://doi.org/10.1186/s12888-017-1485-x

Priebe, S., Bremner, S.A., Lauber, C., Henderson, C. & Burns, T. (2016). Financial incentives to improve adherence to antipsychotic maintenance medicationin non-adherent patients: a cluster randomised controlled trial. Health Technology Assessment, 20 (70). pp. 1-122. ISSN 1366-5278 DOI: 10.3310/hta20700

My source:

Gillon (below) highlights a debate that is ongoing and even more acute given the ethical challenges of today. Interesting also that in 1994 attention to scope could provide a level of assurance(?):

Gillon, R. Medical ethics: four principles plus attention to scope. BMJ. 1994;309(6948):184–8.


Friday, April 14, 2017

Sunday, November 23, 2014

Antipsychotics & Dementia: Managing medications (across Hodges' model)

individual
INTERPERSONAL : SCIENCES
humanistic ------------------------------------------- mechanistic
SOCIOLOGY : POLITICAL
group
person-centered care, communication

diagnosis
medication management
assessment - review
premature deaths, stroke
side-effects
observation
Anti-psychotics:
Traditional - 1st generation
Atypical - 2nd generation
de-prescribing
pain, analgesia, 
research
anti-depressant
cholinesterase inhibitors
titration
trial reduction
avoid benzodiazepines if possible
Team working, collaborative care, family
nursing homes
challenging behaviours -
shouting, aggression, psychosis, agitation
Behavioural and psychological symptoms of dementia (BPSD)
psychosocial interventions, reassuring staff, knowledge and skills
Policy, Reports, Governance, Audit, Consent, Capacity, Consultation, Multi-disciplinary approach, institutions, choice

My source: AlzheimersAustralia via twitter
https://www.dementia.org.au/

Saturday, May 14, 2011

C4 News researching anti-psychotic drugs in people with learning disabilities, inc. children and young people

Channel 4 News is researching the use of anti-psychotic drugs to control challenging or difficult behaviour in people with learning disabilities, including children and young people.

If this is an issue which affects you (or those you care for) or if you would like to share your views or experiences, in confidence, then please do get in touch with Philip Carter on -

... email at pc at pacarter.com

(Dementia is also an issue for people living with learning disabilities and their families. PJ)

My source: The Choice Forum - by the Foundation for People with Learning Disabilities

http://www.learningdisabilities.org.uk

Monday, April 25, 2011

Antipsychotics: person centered care vs roots and branches

When I visit one of the nursing homes in my area, I invariably have specific appointments in mind. Mr Smith or Mrs Brown have been referred, or are already known to community mental health services. Working in an advisory / consultancy / educational capacity other individuals are brought to my attention and this continues the person centered focus - at least at this level.

Keeping things person centered beyond that in assessment, care planing and intervention - is the real challenge. Actually there is another: even where staff are 'trained' and you observe staff -:- resident interactions you often see that (as for us all) there remain key things to learn.

I've visited a few homes to try to jump start an audit of antipsychotics and other drugs that can be so damaging to older adults - potentially fatal in fact as per evidence based findings and reporting in the media:

About 145,000 people with dementia are wrongly being prescribed powerful anti-psychotic medication which causes around 1,800 deaths a year ... The Times
The problem is recognized now as per the Department of Health's (2009) report:


The risks, care management and quality of life issues that arise have prompted some homes / organisations to pursue this internally. My manager Christine and I are working to put a 'pack' together and make connections with colleagues working in residential care / nursing home liaison.

It is essential to check that there is consistency, compliance and that reviews are comprehensive. What blood tests have been completed and exactly when? Have next-of-kin been made aware of the potential side-effects? How skilled are staff in dealing with these acute care challenges? Is there a need to 'fix' the care environment? Is this placement - despite being the individual's home - still appropriate? What specific staff awareness is needed to support any shared care protocol that is put in place?

The point here is that it can be surprising the drugs that do come to our attention. People move in from out of area; some individuals are self-funding so they may by-pass formal services; others are seen by locum doctors / out of hours services and subsequent follow-up may be missed. ...

So here it's not about Mr Smith or Mrs Brown in the first instance, even though that's the expectation when I first arrive. Clearly, this is going to take a dedicated approach away from the personal care problem solving - solution finding (fire-fighting!).

The summary care record could be a great help here and I wonder about searches conducted within primary care GP systems. IT systems aside, it's about turning up and engaging with the homes around a root and branches review of their Medication Administration Records Sheets (MARS).

Task driven - person centered care!

Monday, November 16, 2009

Dementia, Drugs, Nursing by Degr[EE]s and Care Transitions

Of all the policy issues that government faces the care of an ageing population is irresistible in demanding attention. This one will keep tapping MPs, policy makers and families ... on the shoulder. It will constantly cycle through the government's gamut of official papers. In the UK this past week people suffering with dementia and the prescribing of anti-psychotic medication and deaths arising from the same has been highlighted and not for the first time.

Whilst my spare time web attention is also given to nursing IT and socio-technical matters, as an NHS community mental health nurse these vulnerable individuals are the primary focus of my work and that of my colleagues. There are three strands to the current role - in brief:

  • Nursing home liaison - dedicated to specific homes;
  • assessment, intervention and subsequent review;
  • working with social services integration project duty desk.
Drugs are of course a day-to-night constant for all nurses, with the addition of debate across all the knowledge domains of Hodges' model - that is interpersonal, sciences, sociology and political domains of knowledge. We have witnessed this in the scientific evidence of substance misuse and the government misuse of drugs advisory group 'difficulties' and now this issue which is professionally closer to home: right on the doorstep in fact.

'Home' is the operative word as many of the people concerned reside in residential care and nursing home facilities. Let's scratch the surface of what we already know:
  • These people can be very confused, vulnerable, they may be agitated and not easily reassured and placated without repeated skilled intervention.
  • Facilities are subject to inspection and care standards.
  • Many do not have an advocate in the sense of a family member who visits at least weekly and will challenge and question care and prescribing.
  • Older people may already be on several drugs (polypharmacology) due to other chronic health problems.
  • There is still a disconnect (holistic gap!) between the interdependence between mental - physical health problems.
  • These facilities are that individual's home - they continue to live and hence age there.
  • Homes get attached to their residents; in the best homes they (and their relatives and friends) become part of a greatly extended family.
  • For confused people there is a potential community (albeit a closed one) that people can participate in or choose to stay in their room. This space, the freedom of movement it affords - toing-and-froing - should itself be subject to history taking and ongoing assessment.
  • The quality of this community depends on the core staff and additional skills seen as essential by the organisation and care standards, e.g. activities coordinators, residents committees that also engage family, friends.
  • NVQs and mandatory training in the sector is making a positive difference.
  • There remains a high level of staff turnover.
  • Some homes are dual-registered catering for nursing care with another floor for dementia care (does a 1st or 2nd floor provide secure access to a garden in the summer?).
  • Homes rely greatly on the specialist services of local community mental health service, also given the placement of people in homes 'out of area' this involvement may be more remote and subject to varying degrees of engagement and hence quality.
  • Homes are businesses and the movement of clients incurs changes in income.
  • The quality and standards of architecture and design for residential accommodation has seen great strides in the past decade.
The bottom line (no pun intended) is the need for macro-management in terms of multidisciplinary team input; that is, primary care, modern matron, mental health and micro-management in terms of personalised care with regular review of physical and mental well-being and medication.

As government's of all persuasion utter the mantra of education! education! education! - this must be heard in the residential and nursing home care sector. The good news is that standards, competencies and the quality of care in the sector are improving; but to education we must add environment! environment! environment! As someone who appreciates aesthetics in design we should all be aware of the seductive properties of newly designed and furnished nursing homes (new carpets plus brand new flat screen LCD TVs does not automatically mean multi-dimensional care).

The counterpoint to this are the long stay, geriatric wards of old (c. 1977-1984) and the reaction of family friends when they first walked through the (three) doors.

They were distraught.

In time they came to appreciate the efforts of the staff and the importance of the knowledge, skills and attitude of the ward team. They could understand and see what staff were trying to achieve regards individualised care. Many responded to the open invitation to be part of the team, to get involved. Yes, the environment was far from 'right' (it was terrible), but it's the people on all sides of the care equation that count. It is the same today, but if the care environment is no longer appropriate then people should be moved to a place were their care needs can be met without recourse to anti-psychotic medication. That is why initial and ongoing person-centred assessment is very important.

It is very difficult to predict future needs and yet trying to anticipate them is the primary nursing challenge. If life is a book, then the turning of the page that ends one chapter and starts a-new is a non-trivial transition. That said and make no mistake, it is not for dramatic effect that we describe the behaviour of some individuals as challenging. Drugs are a tool and like all tools it is how they are used in assuring the highest standards of care, retaining personal dignity and maximising whatever quality of life an individual can achieve. Accounting for care interventions including medication is critical. If due diligence cannot be effectively applied in the financial sector then perhaps there is scope for due diligence in the care of older adults*?

*Some clients are under 65 years of age.